Gene Expression Changes Induced by Trypanosoma cruzi Shed Microvesicles in Mammalian Host Cells: Relevance of tRNA-Derived Halves
Figure 2
Profile of transcriptomic changes in HeLa cells cocultured with EVs secreted by T. cruzi. HeLa cells were exposed to 160 ng of EVs fraction for two hours and analyzed at different time points. (a) Profile of upregulated (upper panel) and downregulated (bottom panel) genes at different times. (b) Cluster analysis of HeLa regulated genes (FC ≥ 3) at different time points (red: underexpressed; green: overexpressed). Experiments were performed by duplicate on three independent samples.
