Research Article

MTHFR Gene Polymorphism and Age of Onset of Schizophrenia and Bipolar Disorder

Table 1

Clinical data of the control, bipolar, and schizophrenia groups.

   Control
(149)
Bipolar
(134)
Schizophrenia
(103)
Significance

Sex
 Female (%)73 (49.0%)62 (46.3%)35 (34%) = 5.983
= 0.051
 Male (%)76 (51.0%)72 (53.7%)68 (66%)
Residence
 Urban73 (49%)64 (47.8%)55 (53.4%) = 0.794
= 0.672
 Rural76 (51%)70 (52.2%)48 (46.6%)
Family History
 Negative149 (100%)78 (58.2%)67 (65%) = 77.44
= 0.000
 Positive56 (41.8%)36 (35%)
Age (Years ± SD)34.3 ± 6.032.2 ± 10.9 33.9 ± 9.4 = 0.015
= 0.903
Age of onset at diagnosis (Years ± SD)20.4 ± 8.320.25 ± 6.4 = 0.122
= 0.9

Data are numbered (%) and mean ± SD.