Cytotoxicity Studies of Novel Combretastatin and Pterostilbene Derivatives

Table 1

The calculation angles between the ortho-nitro group in position 2 and ring of 1a–7a and 1b–7b stilbenes (the optimum structures of 1a–7a and 1b–7b using the DFT B3LYP/6-311++G(2d, p) method were calculated.).

Compound	Angles (°)
1a	37.3/35.0
2a	32.5/32.8*
3a	31.5/31.4
4a	33.2/32.7
5a	37.4/35.4
6a	34.5/34.5
7a	30.7/30.6
1b	32.5/17.1
2b	35.4/14.1
3b	35.5/14.0
4b	34.9/14.4
5b	34.6/14.7
6b	32.9/17.1
7b	23.8/22.3

∗Data from ref. [10].