Gla-Rich Protein Is a Potential New Vitamin K Target in Cancer: Evidences for a Direct GRP-Mineral Interaction

<table>GRP-F1 is upregulated in mineralization-containing breast cancer samples. Levels of GRP-F1, MGP, GGCX, VKOR, OPN, and TNF<i>α</i> gene expression were determined by qPCR in three control mammary gland (MG 1–3) and four breast cancer (BC 1–4) samples and normalized using 18S and GAPDH as housekeeping genes. Expression values are relative to zero and represent the mean of duplicates; standard deviations are indicated.</table>

BioMed Research International

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Figure 5

Figure 5: Gla-Rich Protein Is a Potential New Vitamin K Target in Cancer: Evidences for a Direct GRP-Mineral Interaction 