Curcumin Loaded Microsponges for Colon Targeting in Inflammatory Bowel Disease: Fabrication, Optimization, and In Vitro and Pharmacodynamic Evaluation

Table 2

3² factorial design for preparing curcumin loaded microsponges.

Formulations	Drug; (mg)	PVA; (g)	Eudragit; (mg)	Ethanol; (mL)
F1	800	5	400	5
F2	800	5	600	5
F3	800	5	800	5
F4	800	5	400	6
F5	800	5	600	6
F6	800	5	800	6
F7	800	5	400	7
F8	800	5	600	7
F9	800	5	800	7
F10*	800	5	700	6.5

∗Extra design checkpoint.