Clinical Study

Association between Peripheral Oxidative Stress and White Matter Damage in Acute Traumatic Brain Injury

Table 1

Demographic data of patients with traumatic brain injury (TBI) and healthy controls.

Patients with TBINormal controls

Numbers2424
Sex (male/female)11/1312/121.000
Age (age)42.79 ± 15.5642.67 ± 12.682.0030.164
Serum thiol concentration1.63 ± 0.271.45 ± 0.354.0650.050
Serum TBARS concentration18.24 ± 13.7010.66 ± 3.2446.5580.014*
Initial Glasgow Coma Scale13.74 ± 3.02
Motor deficit3 (12.5%)
Posttraumatic amnesia5 (20.8%)
Seizure0 (0%)
Brief unconsciousness7 (29.2%)
Depressed skull fracture0 (0%)
Pneumocranium4 (16.7%)
Traumatic subarachnoid hemorrhage12 (50%)
Subdural hematoma12 (50%)
Epidural hematoma5 (20.8%)
Parenchymal contusion hematoma0 (0%)
Operation2 (8.3%)
 Ventriculostomy2 (8.3%)
 Craniectomy0 (0%)
 Craniotomy2 (8.3%)
Days of total hospitalization11.70 ± 7.95
Days of intensive care unit3.87 ± 4.51
Newly onset of neurological deficit1 (4.2%)
Deterioration of consciousness2 (8.3%)

Data are demonstrated as means ± standard deviation.
*Significant differences ( ).