Research Article

Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar Aβ1–42 to the Rat Brain

Figure 3

Injection of fAβ 1–42 did not affect performance in the Morris water maze probe test. (a) In the target quadrant, the amyloid-treated animals spent time comparable to controls. (b) fAβ 1–42-injection did not have a significant effect on the number of crossings over where the virtual platform had been in the maze. Each value represents the mean (±S.E.M.) ( rats per group).
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(a)
345305.fig.003b
(b)