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BioMed Research International
Volume 2014 (2014), Article ID 347616, 8 pages
http://dx.doi.org/10.1155/2014/347616
Research Article

Luminal DMSO: Effects on Detrusor and Urothelial/Lamina Propria Function

Faculty of Health Sciences & Medicine, Bond University, Gold Coast, QLD 4229, Australia

Received 7 January 2014; Accepted 19 April 2014; Published 18 May 2014

Academic Editor: Rok Romih

Copyright © 2014 Katrina J. Smith et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. L. Yoost, S. P. Hertweck, and M. Loveless, “Diagnosis and treatment of interstitial cystitis in adolescents,” Journal of Pediatric and Adolescent Gynecology, vol. 25, pp. 162–171, 2012. View at Google Scholar
  2. S. Rais-Bahrami, J. I. Friedlander, A. S. Herati, M. A. Sadek, M. Ruzimovsky, and R. M. Moldwin, “Symptom profile variability of interstitial cystitis/painful bladder syndrome by age,” BJU International, vol. 109, no. 9, pp. 1356–1359, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. R. M. Moldwin, R. J. Evans, E. J. Stanford, and M. T. Rosenberg, “Rational approaches to the treatment of patients with interstitial cystitis,” Urology, vol. 69, no. 4, pp. S73–S81, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. L. M. French and N. Bhambore, “Interstitial cystitis/painful bladder syndrome,” American Family Physician, vol. 83, no. 10, pp. 1175–1181, 2011. View at Google Scholar · View at Scopus
  5. B. H. Stewart, L. Persky, and W. S. Kiser, “The use of dihyl sulfoxide (DMSO) in the treatment of interstitial cystitis,” Journal of Urology, vol. 98, no. 6, pp. 671–672, 1967. View at Google Scholar · View at Scopus
  6. E. Kelada and A. Jones, “Interstitial cystitis,” Archives of Gynecology and Obstetrics, vol. 275, no. 4, pp. 223–229, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Hohlbrugger and P. Lentsch, “Intravesical ions, osmolality and pH influence the volume pressure response in the normal rat bladder, and this is more pronounced after DMSO exposure,” European Urology, vol. 11, no. 2, pp. 127–130, 1985. View at Google Scholar · View at Scopus
  8. J. F. Borzelleca, T. M. Harris, and S. Bernstein, “The effect of dimethylsulfoxide on the permeability of the urinary bladder,” Investigative Urology, vol. 6, no. 1, pp. 43–52, 1968. View at Google Scholar · View at Scopus
  9. A. A. Gurtovenko and J. Anwar, “Ion transport through chemically induced pores in protein-free phospholipid membranes,” The Journal of Physical Chemistry B, vol. 111, no. 47, pp. 13379–13382, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. A. A. Gurtovenko and J. Anwar, “Modulating the structure and properties of cell membranes: the molecular mechanism of action of dimethyl sulfoxide,” The Journal of Physical Chemistry B, vol. 111, no. 35, pp. 10453–10460, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. L. A. Birder, A. J. Kanai, F. Cruz, K. Moore, and C. H. Fry, “Is the urothelium intelligent?” Neurourology and Urodynamics, vol. 29, no. 4, pp. 598–602, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. M. H. Hawthorn, C. R. Chapple, M. Cock, and R. Chess-Williams, “Urothelium-derived inhibitory factor(s) influences on detrusor muscle contractility in vitro,” British Journal of Pharmacology, vol. 129, no. 3, pp. 416–419, 2000. View at Google Scholar · View at Scopus
  13. L. A. Birder, A. J. Kanai, and W. C. de Groat, “DMSO: effect on bladder afferent neurons and nitric oxide release,” The Journal of Urology, vol. 158, no. 5, pp. 1989–1995, 1997. View at Google Scholar
  14. L. A. Birder and W. C. de Groat, “Mechanisms of disease: involvement of the urothelium in bladder dysfunction,” Nature Clinical Practice Urology, vol. 4, no. 1, pp. 46–54, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. D. J. Sellers and R. Chess-Williams, “Muscarinic agonists and antagonists: effects on the urinary bladder,” Handbook of Experimental Pharmacology, vol. 208, pp. 375–400, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Cheng, K. J. Mansfield, S. L. Sandow, P. Sadananda, E. Burcher, and K. H. Moore, “Porcine bladder urothelial, myofibroblast, and detrusor muscle cells: characterization and ATP release,” Frontiers in Pharmacology, vol. 2, article 27, 2011. View at Publisher · View at Google Scholar
  17. A. G. H. Santoso, I. A. B. Sonarno, N. A. B. Arsad, and W. Liang, “The role of the urothelium and ATP in mediating detrusor smooth muscle contractility,” Urology, vol. 76, no. 5, pp. 1267.e7–1267.e12, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. L. A. Birder, H. Z. Ruan, B. Chopra et al., “Alterations in P2X and P2Y purinergic receptor expression in urinary bladder from normal cats and cats with interstitial cystitis,” American Journal of Physiology—Renal Physiology, vol. 287, no. 5, pp. F1084–F1091, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. V. Kumar, C. R. Chapple, A. M. Surprenant, and R. Chess-Williams, “Enhanced adenosine triphosphate release from the urothelium of patients with painful bladder syndrome: a possible pathophysiological explanation,” Journal of Urology, vol. 178, no. 4, pp. 1533–1536, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. Sun and T. C. Chai, “Role of purinergic signaling in voiding dysfunction,” Current Bladder Dysfunction Reports, vol. 5, pp. 219–224, 2010. View at Google Scholar
  21. S. W. Shirley, B. H. Stewart, and S. Mirelman, “Dimethyl sulfoxide in treatment of inflammatory genitourinary disorders,” Urology, vol. 11, no. 3, pp. 215–220, 1978. View at Google Scholar · View at Scopus
  22. P. Irwin, “Bladder pain syndrome/interstitial cystitis,” in Medical Therapy in Urology, I. Shergill, M. Arya, P. Grange, and A. R. Mundy, Eds., pp. 121–132, Springer, 2010. View at Google Scholar
  23. L. A. Birder, M. Ruggieri, M. Takeda et al., “How does the urothelium affect bladder function in health and disease?: ICI-RS 2011,” Neurourology and Urodynamics, vol. 31, no. 3, pp. 293–299, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. Y. Sun and T. C. Chai, “Effects of dimethyl sulphoxide and heparin on stretch-activated ATP release by bladder urothelial cells from patients with interstitial cystitis,” BJU International, vol. 90, no. 4, pp. 381–385, 2002. View at Publisher · View at Google Scholar · View at Scopus
  25. L. Templeman, C. R. Chapple, and R. Chess-Williams, “Urothelium derived inhibitory factor and cross-talk among receptors in the trigone of the bladder of the pig,” Journal of Urology, vol. 167, no. 2, pp. 742–745, 2002. View at Google Scholar · View at Scopus
  26. R. Chess-Williams, B. Cross, and C. Chapple, “Depressed inhibition of detrusor contractions by the urothelium in the human neurogenic overactive bladder,” Neurourology and Urodynamics, vol. 28, pp. 869–870, 2009. View at Google Scholar
  27. P. Sadananda, R. Chess-Williams, and E. Burcher, “Contractile properties of the pig bladder mucosa in response to neurokinin A: a role for myofibroblasts?” British Journal of Pharmacology, vol. 153, no. 7, pp. 1465–1473, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Moro, J. Uchiyama, and R. Chess-Williams, “Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol,” Urology, vol. 78, no. 6, pp. 1442.e9–1442.e15, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. P. Tyagi, V. C. Hsieh, N. Yoshimura, J. Kaufman, and M. B. Chancellor, “Instillation of liposomes vs dimethyl sulphoxide or pentosan polysulphate for reducing bladder hyperactivity,” BJU International, vol. 104, no. 11, pp. 1689–1692, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. A. Sokol and E. Sokol, Interstitial Cystitis and Chronic Pelvic Pain: General Gynecology: The Requisites in Obstetrics and Gynecology, Elsevier, St Louis, Mo, USA, 2007.