Research Article

A Standardized Critical Size Defect Model in Normal and Osteoporotic Rats to Evaluate Bone Tissue Engineered Constructs

Figure 1

Osteosynthesis system consisting of a PEEK plate, 23 mm (length) × 2 mm (height) × 3 mm (width), which is mounted on the rat femur by six 0.7 × 5.2 mm angular stable self-tapping screws after predrilling with a 0.65 mm drill bit. To facilitate plate placement and to create a standardized 5 mm defect a combined drill and saw guide is utilized (RatFix, RiSystems).
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