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BioMed Research International
Volume 2014 (2014), Article ID 348647, 6 pages
http://dx.doi.org/10.1155/2014/348647
Research Article

Propolis Varnish: Antimicrobial Properties against Cariogenic Bacteria, Cytotoxicity, and Sustained-Release Profile

1Department of Paediatric Dentistry and Orthodontics, Faculty of Dentistry, Federal University of Minas Gerais, Campus Pampulha, Avenida Presidente Antônio Carlos 6627, 31.270-901 Belo Horizonte, MG, Brazil
2Department of Pharmaceutical Products, Faculty of Pharmacy, Federal University of Minas Gerais, Campus Pampulha, Avenida Presidente Antônio Carlos 6627, 31.270-901 Belo Horizonte, MG, Brazil
3Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Campus Pampulha, Avenida Presidente Antônio Carlos 6627, 31.270-901 Belo Horizonte, MG, Brazil
4Biomedical Engineering Institute (INEB), Porto University and Faculty of Engineering, DEMM, Porto University, Porto, Portugal
5Department of Oral Surgery and Pathology, Faculty of Dentistry, Federal University of Minas Gerais, Campus Pampulha, Avenida Presidente Antônio Carlos 6627, 31.270-901 Belo Horizonte, MG, Brazil

Received 23 February 2014; Revised 6 April 2014; Accepted 22 April 2014; Published 13 May 2014

Academic Editor: Kota V. Ramana

Copyright © 2014 Mariana P. De Luca et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. E. Petersen, “The world oral health report 2003: continuous improvement of oral health in the 21st century-the approach of the WHO global health programme,” Community Dentistry and Oral Epidemiology, vol. 31, no. 1, pp. 3–23, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. B. A. Dye, S. Tan, V. Smith et al., “Trends in oral health status: united States, 1988–1994 and 1999–2004,” Vital and Health Statistics, no. 248, pp. 1–92, 2007. View at Google Scholar · View at Scopus
  3. W. H. Bowen and H. Koo, “Biology of Streptococcus mutans derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilms,” Caries Research, vol. 45, no. 1, pp. 69–86, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. L. G. Petersson, K. Magnusson, H. Andersson, B. Almquist, and S. Twetman, “Effect of quarterly treatments with a chlorexidine and a fluoride varnish on approximal caries in caries-susceptible teenagers: a 3-year clinical study,” Caries Research, vol. 34, no. 2, pp. 140–143, 2000. View at Google Scholar · View at Scopus
  5. Q. Zhang, W. H. van Palenstein Helderman, M. A. Van't Hof, and G.-J. Truin, “Chlorhexidine varnish for preventing dental caries in children, adolescents and young adults: a systematic review,” European Journal of Oral Sciences, vol. 114, no. 6, pp. 449–455, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. D. Steinberg, M. Moldovan, and D. Molukandov, “Testing a degradable topical varnish of cetylpyridinium chloride in an experimental dental biofilm model,” Journal of Antimicrobial Chemotherapy, vol. 48, no. 2, pp. 241–243, 2001. View at Google Scholar · View at Scopus
  7. B. A. Cunha, “Antibiotic side effects,” Medical Clinics of North America, vol. 85, no. 1, pp. 149–185, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. B. H. Normark and S. Normark, “Evolution and spread of antibiotic resistance,” Journal of Internal Medicine, vol. 252, no. 2, pp. 91–106, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. S. A. Liberio, A. L. A. Pereira, R. P. Dutra et al., “Antimicrobial activity against oral pathogens and immunomodulatory effects and toxicity of geopropolis produced by the stingless bee Melipona fasciculata Smith,” BMC Complementary and Alternative Medicine, vol. 11, article 108, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. S. A. Libério, A. L. A. Pereira, M. J. A. M. Araújo et al., “The potential use of propolis as a cariostatic agent and its actions on mutans group streptococci,” Journal of Ethnopharmacology, vol. 125, no. 1, pp. 1–9, 2009. View at Google Scholar
  11. A. M. B. Paula, R. T. Gomes, W. K. Santiago, R. S. Dias, M. E. Cortés, and V. R. Santos, “Susceptibility of oral pathogenic bacteria and fungi to brazilian green propolis extract,” Pharmacologyonline, vol. 3, pp. 467–473, 2006. View at Google Scholar
  12. H. C. Van Der Mei, E. Engels, J. De Vries, R. J. B. Dijkstra, and H. J. Busscher, “Chitosan adsorption to salivary pellicles,” European Journal of Oral Sciences, vol. 115, no. 4, pp. 303–307, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. T. Uysal, M. D. Akkurt, M. Amasyali et al., “Does a chitosan-containing dentifrice prevent demineralization around orthodontic brackets?” Angle Orthodontist, vol. 81, no. 2, pp. 319–325, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Liu, B. Chen, Z. Mao, and C. Gao, “Chitosan nanoparticles for loading of toothpaste actives and adhesion on tooth analogs,” Journal of Applied Polymer Science, vol. 106, no. 6, pp. 4248–4256, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. R. D. Wojtyczka, A. Dziedzic, D. Idzik et al., “Susceptibility of Staphylococcus aureus clinical isolates to propolis extract alone or in combination with antimicrobial drugs,” Molecules, vol. 18, no. 8, pp. 9623–9640, 2013. View at Publisher · View at Google Scholar
  16. A. A. Righi, G. Negri, and A. Salatino, “Comparative chemistry of propolis from eight brazilian localities,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 267878, 14 pages, 2013. View at Publisher · View at Google Scholar
  17. A. C. H. F. Sawaya, I. Barbosa da Silva Cunha, and M. C. Marcucci, “Analytical methods applied to diverse types of Brazilian propolis,” Chemistry Central Journal, vol. 5, no. 1, article 27, 2011. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Fani and J. J. Kohanteb, “Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria,” Journal of Oral Science, vol. 54, no. 1, pp. 15–21, 2012. View at Google Scholar
  19. L. C. Galvão, V. F. Furletti, S. M. Bersan et al., “Antimicrobial activity of essential oils against Streptococcus mutans and their antiproliferative effects,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 751435, 12 pages, 2012. View at Publisher · View at Google Scholar
  20. J. Cornish, K. E. Callon, C. Q.-X. Lin et al., “Trifluoroacetate, a contaminant in purified proteins, inhibits proliferation of osteoblasts and chondrocytes,” American Journal of Physiology—Endocrinology and Metabolism, vol. 277, no. 5, part 1, pp. E779–E783, 1999. View at Google Scholar · View at Scopus
  21. C. S. Funari and V. O. Ferro, “Análise de própolis,” Ciênc Tecnol Aliment, vol. 26, no. 1, pp. 171–178, 2006. View at Google Scholar
  22. P. Costa and J. M. Sousa Lobo, “Modeling and comparison of dissolution profiles,” European Journal of Pharmaceutical Sciences, vol. 13, no. 2, pp. 123–133, 2001. View at Publisher · View at Google Scholar · View at Scopus
  23. J. M. Sforcin and V. Bankova, “Propolis: is there a potential for the development of new drugs?” Journal of Ethnopharmacology, vol. 133, no. 2, pp. 253–260, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. V. Bankova, “Recent trends and important developments in propolis research,” Evidence-Based Complementary and Alternative Medicine, vol. 2, no. 1, pp. 29–32, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. S. A. D. C. Duailibe, A. G. Gonçalves, and F. J. M. Ahid, “Effect of a propolis extract on Streptococcus mutans counts in vivo,” Journal of Applied Oral Science, vol. 15, no. 5, pp. 420–423, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. R. A. Ccahuana-Vásquez and J. A. Cury, “S. mutans biofilm model to evaluate antimicrobial substances and enamel demineralization,” Brazilian Oral Research, vol. 24, no. 2, pp. 135–141, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. E.-M. Decker, C. Von Ohle, R. Weiger, I. Wiech, and M. Brecx, “A synergistic chlorhexidine/chitosan combination for improved antiplaque strategies,” Journal of Periodontal Research, vol. 40, no. 5, pp. 373–377, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Fujiwara, Y. Hayashi, and N. Ohara, “Inhibitory effect of water-soluble chitosan on growth of Streptococcus mutans,” New Microbiologica, vol. 27, no. 1, pp. 83–86, 2004. View at Google Scholar · View at Scopus
  29. T. Kean and M. Thanou, “Biodegradation, biodistribution and toxicity of chitosan,” Advanced Drug Delivery Reviews, vol. 62, no. 1, pp. 3–11, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. A. Al-Shaher, J. Wallace, S. Agarwal, W. Bretz, and D. Baugh, “Effect of propolis on human fibroblasts from the pulp and periodontal ligament,” Journal of Endodontics, vol. 30, no. 5, pp. 359–361, 2004. View at Google Scholar · View at Scopus
  31. F. Li, S. Awale, Y. Tezuka, and S. Kadota, “Cytotoxic constituents of propolis from Myanmar and their structure-activity relationship,” Biological and Pharmaceutical Bulletin, vol. 32, no. 12, pp. 2075–2078, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. L. B. Rodrigues, H. F. Leite, M. I. Yoshida, J. B. Saliba, A. S. C. Junior, and A. A. G. Faraco, “In vitro release and characterization of chitosan films as dexamethasone carrier,” International Journal of Pharmaceutics, vol. 368, no. 1-2, pp. 1–6, 2009. View at Publisher · View at Google Scholar · View at Scopus