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BioMed Research International
Volume 2014, Article ID 349034, 7 pages
Clinical Study

Spinal Anesthesia for Knee Arthroscopy Using Isobaric Bupivacaine and Levobupivacaine: Anesthetic and Neuroophthalmological Assessment

1Department of Anesthesia, University Hospital Virgen de la Arrixaca, Ctra. Madrid-Cartagena, s/n, El Palmar, 30120 Murcia, Spain
2Department of Ophthalmology and Optometry, School of Medicine, University of Murcia, Avenida Intendente Jorge Palacios 1, 30003 Murcia, Spain
3Department of Ophthalmology, General University Hospital Reina Sofia, Avenida Intendente Jorge Palacios 1, 30003 Murcia, Spain
4Department of Anesthesia, University Hospital La Fe, Bulevar del Sur, 46026 Valencia, Spain
5Department of Ophthalmology, University School of Medicine, University of Valencia, Avenida Blasco Ibáñez 15-17, 46010 Valencia, Spain

Received 22 July 2013; Revised 29 October 2013; Accepted 12 November 2013; Published 20 February 2014

Academic Editor: Shahrzad Bazargan-Hejazi

Copyright © 2014 Monica del-Rio-Vellosillo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. The aim of the study was to compare the sensory, motor, and neuroophthalmological effects of isobaric levobupivacaine and bupivacaine when intrathecally administered. Materials and Methods. A prospective, double-blind, randomized study with 60 ASA grade I-II patients aged 18–65 years awaiting knee arthroscopy under spinal anesthesia. Patients received 12.5 mg of isobaric bupivacaine or levobupivacaine. Several features were recorded. Results. No significant intergroup differences were observed for ASA classification, time to micturate, demographic data, surgery duration, and patient/surgeon satisfaction. Similar hemodynamic parameters and sensory/motor blockade duration were found for both groups. There were no neuroophthalmological effects in either group. Sensory ( ) and motor blockade onset ( ) was faster in the bupivacaine group. T6 (T2–T12) and T3 (T2–T12) were the highest sensory block levels for the levobupivacaine and bupivacaine groups, respectively ( ). It took less time to regain maximum motor blockade in the bupivacaine group ( ), and the levobupivacaine group required use of analgesia earlier ( ). Conclusions. Isobaric bupivacaine and levobupivacaine are analogous and well-tolerated anesthetics for knee arthroscopy. However, for bupivacaine, sensory and motor blockade onset was faster, and greater sensory blockade with a longer postoperative painless period was achieved.