Effect of Alocasia indica Tuber Extract on Reducing Hepatotoxicity and Liver Apoptosis in Alcohol Intoxicated Rats

Table 1

Effect of EEAIT on the biochemical parameters in ethanol-induced hepatotoxicity in rats.

Parameter	C	E	E + AI200	E + AI400	E + silymarin	Kruskal-Wallis nonparametric ANOVA
ALT (U/L)	21.4±3.4	37.8±4.5^a∗∗	30.2±2.6^b∗	25.8±2.4^c∗∗d∗	24.2±1.7^∗∗	𝑃<0.01
AST (U/L)	26.6±3.8	40.6±3.4^a∗∗	36.4±4.4^b∗	26.7±6.1^c∗∗d∗	26.6±4.4^∗∗	𝑃<0.01
γGT (U/L)	7.6±1.0	13.78±2.3^a∗∗	11.16±2.2^b∗	9.1±0.9^c∗∗d∗	8.5±1.4^∗∗	𝑃<0.01
Bilirubin (U/L)	0.17±0.04	0.75±0.1^a∗∗	0.49±0.05^b∗∗	0.26±0.06^c∗∗d∗∗	0.19±0.02^∗∗	𝑃<0.001
NO (µM/mg protein)	58.6±7.0	79.4±7.7^a∗∗	64.6±2.1^b∗∗	62.2±3.7^c∗∗d∗	60.3±2.3^∗∗	𝑃<0.01
GSH (mM/mg protein)	9.3±0.86	7.13±0.46^a∗∗	7.5±0.65^bNS	8.05±0.56^c∗d∗	9.1±0.8^∗∗	𝑃<0.01
MDA (mM/mg protein)	77.9±2.8	99.3±0.88^a∗∗	89.4±3.1^b∗∗	81.7±1.5^c∗∗d∗∗	78.7±1.3^∗∗	𝑃<0.001
SOD (U/mg protein)	0.3±0.004	0.31±0.002^a∗∗	0.34±0.006^b∗∗	0.35±0.004^c∗∗d∗∗	0.34±0.001^∗∗	𝑃<0.001
CAT (U/mg protein)	153.8±11.4	50.6±28.1^a∗∗	69.4±36.4^bNS	125.6±17.8^c∗∗d∗∗	149.7±12.3^∗∗	𝑃<0.01

Significance level based on Kruskal-Wallis nonparametric ANOVA and Mann Whitney 𝑈 multiple comparisons tests—^acontrol versus ethanol, ^bethanol versus AI200, ^cethanol versus AI400, ethanol versus AI400, and ^dAI200 versus AI400. ^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001, NS: not significant (mean ± SD).