BioMed Research International / 2014 / Article / Fig 5

Research Article

BDNF Increases Survival and Neuronal Differentiation of Human Neural Precursor Cells Cotransplanted with a Nanofiber Gel to the Auditory Nerve in a Rat Model of Neuronal Damage

Figure 5

Graphs illustrating the quantification of numbers of GFP+ HNPCs, differentiated cells, and cells with neuronal outgrowths. (a) Total number of GFP+ HNPCs. Groups 2 and 3 had significantly better cell survival compared to Group 1 (). After 3 weeks the majority of the surviving cells were observed in the AN whereas after 6 weeks the majority of the cells were found in the BS. No cells were found in Group 4 (data not shown). (b) Number of double-labeled (GFP and TUJ1) differentiated cells. Groups 2 and 3 had significantly more differentiated cells than Group 1 (). After six weeks, the majority of the differentiated cells were found in the BS. (c) Number of differentiated cells with outgrowth of fibers. Groups 2 and 3 had significantly more cells with fiber outgrowth as compared to Group 1 ().

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.