The Association of Toll-Like Receptor 4 Polymorphism with Hepatitis C Virus Infection in Saudi Arabian Patients

Table 3

Genotypic distribution of TLR4 SNPs between chronic HCV patients (CHC) and patients with liver cirrhosis (Cirr).

SNPs	Genotype/allele distribution	Chronic HCV patients	Patients with liver cirrhosis	OR (95% CI.)		value
rs4986791	CC	332 (94.0%)	77 (89.5%)	1.0000 (Ref.)
	CT	22 (6.0%)	9 (10.5%)	1.764 (0.781–3.982)	1.91	0.167
	TT	0 (0%)	0 (0%)	nan
	C	686 (96.9%)	163 (94.8%)	1.0000 (Ref.)
	T	22 (3.1%)	9 (5.2%)	1.722 (0.778–3.809)	1.84	0.175
	TT + CT versus CC			1.764 (0.781–3.982)	1.91	0.167
	TT versus CT + CC			nan
rs4986790	AA	323 (91.8%)	75 (86.2%)	1.0000 (Ref.)
	AG	29 (8.2%)	12 (13.8%)	1.782 (0.869–3.654)	2.54	0.111
	GG	0 (0%)	0 (0%)	nan
	A	675 (95.9%)	162 (93.1%)	1.0000 (Ref.)
	G	29 (4.1%)	12 (6.9%)	1.724 (0.861–3.452)	2.42	0.120
	GG versus AG + AA			nan
	GG + AG versus AA			1.782 (0.869–3.654)	2.54	0.110

Risk allele marked in bold letters.