Inhibition of Nitric Oxide Synthase Prevents Muscarinic and Purinergic Functional Changes and Development of Cyclophosphamide-Induced Cystitis in the Rat

Figure 5

Bladder wall thickness (a), mucosa thickness (b), and ratio of mast cell occurrence in the detrusor (c), expressed as % of total number of mast cells (𝑛=3 in all groups) in saline-treated (white) and CYP-treated (black) rats. The vertical bars represent the SEM. ^∗ denotes 𝑃<0.05, ^∗∗𝑃<0.01 and ^∗∗∗𝑃<0.001 (comparisons between saline- and CYP-treated groups). ## denotes 𝑃<0.01 (comparison with saline pretreated and CYP-treated group).

(a)

(b)

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