Review Article
Predictive Symptoms and Signs of Severe Dengue Disease for Patients with Dengue Fever: A Meta-Analysis
Table 1
Basic features of the eligible studies.
| | Author (publication year) | Study design | Population | Gender | Vomiting/nausea | Bleeding | Headache | Abdominal pain | Retroorbital pain | Rashes | Diarrhea | Hepatomegaly | Lethargy | Tourniquet test | | DF (M/F) | SD (M/F) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) | DF (Y/N) | SD (Y/N) |
| | Ahmed et al. (2001) [17] | Prospective | Children | — | — | 4/22 | 5/41 | 16/10 | 46/0 | 22/4 | 34/12 | — | — | 7/19 | 10/36 | 3/23 | 24/22 | 6/20 | 8/38 | 0/26 | 36/10 | — | — | — | — | | Narayanan et al. (2002) [21] | Prospective | Children | 22/21 | 9/7 | 34/9 | 15/1 | 23/20 | 16/0 | 13/30 | 4/12 | 10/33 | 4/12 | 3/40 | 4/12 | 4/39 | 1/15 | — | — | 19/24 | 12/4 | 11/32 | 3/13 | 5/38 | 9/7 | | Endy et al. (2002) [19] | Prospective | Children | — | — | 44/89 | 14/5 | 2/130 | 1/18 | 82/50 | 14/5 | 20/111 | 6/13 | — | — | 6/125 | 1/18 | 5/127 | 1/18 | — | — | 43/89 | 6/13 | — | — | | Phuong et al. (2004) [22] | Prospective | Children | — | — | 178/134 | 234/85 | 56/256 | 36/283 | 140/167 | 88/230 | 156/156 | 234/84 | — | — | — | — | — | — | — | — | — | — | 106/166 | 128/145 | | Carlos et al. (2005) [18] | Prospective | Children | 143/96 | 72/48 | — | — | 11/221 | 6/105 | — | — | 69/168 | 51/68 | — | — | — | — | — | — | — | — | 0/238 | 4/115 | — | — | | Shah et al. (2006) [9] | Prospective | Children | — | — | 11/0 | 87/2 | 0/11 | 68/21 | 11/0 | 87/2 | 9/2 | 87/2 | 11/0 | 87/2 | — | — | — | — | 0/11 | 77/12 | 11/0 | 87/2 | 10/1 | 15/15 | | Malavige et al. (2006) [23] | Prospective | Adult | — | — | 18/15 | 51/24 | 5/28 | 37/38 | 26/7 | 45/30 | 3/30 | 14/61 | — | — | — | — | 7/26 | 24/51 | 10/23 | 39/36 | — | — | — | — | | Lee et al. (2006) [24] | Retrospective | Both | 177/235 | 119/113 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | | Riaz et al. (2009) [27] | Cross-sectional | Both | — | — | 134/35 | 83/26 | 6/163 | 89/20 | 23/146 | 13/96 | 85/84 | 61/48 | 0/169 | 1/108 | 55/114 | 37/72 | 10/159 | 2/107 | 1/168 | 1/108 | — | — | — | — | | Lee et al. (2009) [25] | Retrospective | Adult | 1183/672 | 53/29 | 604/1251 | 29/53 | — | — | 606/1249 | 16/66 | 252/1603 | 14/68 | 5/1850 | 0/82 | 887/968 | 49/33 | — | — | — | — | — | — | — | — | | Priyadarshini et al. (2010) [10] | Prospective | Both | — | — | 90/69 | 44/18 | — | — | 101/58 | 33/29 | 29/130 | 31/31 | 34/125 | 2/60 | 31/128 | 26/36 | — | — | — | — | — | — | — | — | | Khan et al. (2010) [8] | Retrospective | Both | 99/62 | 30/10 | 93/68 | 27/13 | 6/155 | 29/11 | 21/140 | 2/38 | 6/80 | 1/10 | — | — | 44/117 | 31/9 | 26/135 | 5/35 | — | — | — | — | — | — | | Giraldo et al. (2011) [7] | Retrospective | Children | 77/74 | 16/14 | 96/55 | 23/7 | 51/100 | 14/16 | 92/59 | 17/13 | 78/73 | 22/8 | 18/133 | 4/26 | 63/88 | 16/14 | 29/122 | 5/25 | 27/124 | 7/23 | 54/97 | 20/10 | — | — | | Falconar et al. (2012) [20] | Prospective | Both | — | — | 13/15 | 4/1 | 13/28 | 5/0 | — | — | 0/28 | 5/0 | 22/6 | 4/1 | — | — | — | — | 0/28 | 2/3 | — | — | 8/20 | 5/0 | | Karoli et al. (2012) [26] | Cross-sectional | Both | — | — | — | — | 13/83 | 42/0 | 77/19 | 28/14 | — | — | — | — | 26/70 | 12/30 | — | — | 47/49 | 25/17 | — | — | — | — | | Sirivichayakul et al. (2012) [11] | Prospective | Children | — | — | 95/28 | 32/2 | — | — | 107/16 | 25/9 | 59/64 | 25/9 | 35/88 | 13/21 | 53/70 | 18/16 | 21/102 | 17/17 | — | — | 23/100 | 6/28 | — | — |
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Note: “M”: male; “F”: female; “Y”: yes, the group has the symptom; “N”: no, the group has no symptom. “—”: no statistics.
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