Differential Protein Network Analysis of the Immune Cell Lineage

Figure 4

Bipartite network representation of immune cell lineages and protein network exemplars. In this bipartite network representation, the protein network exemplars are represented as circles (the names and genes in these exemplar groups are listed in Table 1), and immune cell types represented as square diamonds. A color gradient of degree of the node in the bipartite network ranges from green (lowest) to yellow (intermediate) and red (highest) is represented. Lineage specific exemplars are clearly illustrated in addition to the increasing range of common protein network exemplars. (These two types of patterns are listed in Table 2 and 3, resp.). The protein network exemplars are ordered, 1−10, according to their connectivity to the ten immune cell types in the bipartite network.