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BioMed Research International
Volume 2014, Article ID 364625, 10 pages
http://dx.doi.org/10.1155/2014/364625
Research Article

Potential Mitochondrial Isocitrate Dehydrogenase R140Q Mutant Inhibitor from Traditional Chinese Medicine against Cancers

1Department of Biomedical Informatics, Asia University, Taichung 41354, Taiwan
2School of Medicine, College of Medicine, China Medical University, Taichung 40402, Taiwan
3Department of Neurosurgery, China Medical University Hospital, Taichung 40447, Taiwan
4School of Pharmacy, China Medical University, Taichung 40402, Taiwan
5Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 40402, Taiwan

Received 16 February 2014; Revised 4 March 2014; Accepted 4 March 2014; Published 5 June 2014

Academic Editor: Chung Y. Hsu

Copyright © 2014 Wen-Yuan Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Shaily Goyal, Varsha Sharma, and Kishan Gopal Ramawat, “A Review of Biotechnological Approaches to Conservation and Sustainable Utilization of Medicinal Lianas in India,” Biodiversity of Lianas, vol. 5, pp. 179–210, 2015. View at Publisher · View at Google Scholar
  • Tianfang Ma, Fangxia Zou, Stefan Pusch, Yungen Xu, Andreas von Deimling, and Xiaoming Zha, “Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective,” Journal of Medicinal Chemistry, 2018. View at Publisher · View at Google Scholar
  • Ezequiel Iván Juritz, Juan Pablo Bascur, Daniel Eduardo Almonacid, and Fernando Danilo González-Nilo, “Novel Insights for Inhibiting Mutant Heterodimer IDH1wt-R132H in Cancer: An In-Silico Approach,” Molecular Diagnosis & Therapy, 2018. View at Publisher · View at Google Scholar
  • Jian Wang, Zhan-guo Zhang, Ze-yang Ding, Wei Dong, Hui-fang Liang, Liang Chu, Bi-xiang Zhang, and Xiao-ping Chen, “IDH1 mutation correlates with a beneficial prognosis and suppresses tumor growth in IHCC,” Journal of Surgical Research, vol. 231, pp. 116–125, 2018. View at Publisher · View at Google Scholar
  • Jean Loup Huret, and Philippe Dessen, “IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial)6,” Atlas of Genetics and Cytogenetics in Oncology and Haematology, vol. 22, no. 4, pp. 123–137, 2018. View at Publisher · View at Google Scholar
  • Hueng-Chuen Fan, Chuan-Mu Chen, Ching-Shiang Chi, Jeng-Dau Tsai, Kuo-Liang Chiang, Yu-Kang Chang, Shinn-Zong Lin, and Horng-Jyh Harn, “Targeting Telomerase and ATRX/DAXX Inducing Tumor Senescence and Apoptosis in the Malignant Glioma,” International Journal of Molecular Sciences, vol. 20, no. 1, pp. 200, 2019. View at Publisher · View at Google Scholar