Research Article

Potential Mitochondrial Isocitrate Dehydrogenase R140Q Mutant Inhibitor from Traditional Chinese Medicine against Cancers

Figure 2

Binding site of IDH2 R140Q mutant protein defined as the volume of AGI-6780 and root-mean-square deviation value between crystallized structure (orange) and docking pose (violet) of AGI-6780.
364625.fig.002