Research Article

Extracellular Matrix Proteins Expression Profiling in Chemoresistant Variants of the A2780 Ovarian Cancer Cell Line

Table 2

The gene list showing the fold-change in matrix metallopeptidases and related genes in the drug-resistant sublines with respect to the parental A2780 cell line.

Gene
symbol
RefSeQ transcript
ID
Fold-change
C versus P1C versus P2C versus C1C versus C2C versus D1C versus D2C versus T1C versus T2

MMP1NM_00114593811.65NSNSNSNSNSNS10.63
MMP3NM_00242258.85NSNSNSNSNSNSNS
MMP10NM_0024259.84−17.77−16.29NS−12.87NSNS6.92
MMP12NM_002426NSNSNSNSNS10.78NSNS
ADAMTS3NM_014243−7.95NSNSNSNSNSNSNS
ADAM22NM_004194NS8.05NSNSNSNSNSNS
TIMP3NM_000362NSNS50.826.24NSNSNSNS

NS: up- or downregulation between 5 and −5, indicative of changes in expressions that are not statistically significant.