Extracellular Matrix Proteins Expression Profiling in Chemoresistant Variants of the A2780 Ovarian Cancer Cell Line
Table 2
The gene list showing the fold-change in matrix metallopeptidases and related genes in the drug-resistant sublines with respect to the parental A2780 cell line.
Gene symbol
RefSeQ transcript ID
Fold-change
C versus P1
C versus P2
C versus C1
C versus C2
C versus D1
C versus D2
C versus T1
C versus T2
MMP1
NM_001145938
11.65
NS
NS
NS
NS
NS
NS
10.63
MMP3
NM_002422
58.85
NS
NS
NS
NS
NS
NS
NS
MMP10
NM_002425
9.84
−17.77
−16.29
NS
−12.87
NS
NS
6.92
MMP12
NM_002426
NS
NS
NS
NS
NS
10.78
NS
NS
ADAMTS3
NM_014243
−7.95
NS
NS
NS
NS
NS
NS
NS
ADAM22
NM_004194
NS
8.05
NS
NS
NS
NS
NS
NS
TIMP3
NM_000362
NS
NS
50.82
6.24
NS
NS
NS
NS
NS: up- or downregulation between 5 and −5, indicative of changes in expressions that are not statistically significant.