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BioMed Research International
Volume 2014 (2014), Article ID 367268, 9 pages
http://dx.doi.org/10.1155/2014/367268
Research Article

The Structural Modeling of the Interaction between Levofloxacin and the Mycobacterium tuberculosis Gyrase Catalytic Site Sheds Light on the Mechanisms of Fluoroquinolones Resistant Tuberculosis in Colombian Clinical Isolates

1Corporación Para Investigaciones Biológicas—(CIB), Bacteriology and Mycobacteria Unit, Carrera 72a N 78B-141, Medellín, Colombia
2Universidad Pontificia Bolivariana—(UPB), Calle 78b No. 72a-109, Medellín, Colombia
3Escuela de Ingeniería de Antioquia, Km 2 + 200 Vía al Aeropuerto José María Córdova, Envigado, Colombia
4Grupo Interdisciplinario de Estudios Moleculares—(GIEM), Universidad de Antioquia, Calle 67 No. 108-53, Medellín, Colombia
5Equal Opportunity Life Sciences, 1132 Parrish Drive, Rockville, MD 20851, USA

Received 11 October 2013; Accepted 12 February 2014; Published 28 April 2014

Academic Editor: Jakko van Ingen

Copyright © 2014 N. Alvarez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

N. Alvarez, E. Zapata, G. I. Mejía, et al., “The Structural Modeling of the Interaction between Levofloxacin and the Mycobacterium tuberculosis Gyrase Catalytic Site Sheds Light on the Mechanisms of Fluoroquinolones Resistant Tuberculosis in Colombian Clinical Isolates,” BioMed Research International, vol. 2014, Article ID 367268, 9 pages, 2014. doi:10.1155/2014/367268