Notch1 and 4 Signaling Responds to an Increasing Vascular Wall Shear Stress in a Rat Model of Arteriovenous Malformations
Figure 3
The positive immunofluorescence of caspase3 staining in blue in the “nidus” vessels. CD31 was stained positively in red. The positive immunofluorescence of Notch1 and 4 receptors, their ligands Jagged1, Delta1 and 4, and Notch downstream target Hes1 in green in the “nidus” vessels 42 days after AVF formation. L: lumen. Immunohistochemistry, bar = 300 μm.
