Assessment of DNA Damage and Telomerase Activity in Exfoliated Urinary Cells as Sensitive and Noninvasive Biomarkers for Early Diagnosis of Bladder Cancer in Ex-Workers of a Rubber Tyres Industry

Table 4

Comparison of cystoscopy-biopsy with cytology, TRAP, FISH, and comet test results on exfoliated urothelial cells of ex-exposed workers distributed for class of risk.

Subject code	Class of risk	Cystoscopy-biopsy	Urinary
			Cytology	TRAP	FISH	Comet
35	5	Dysplastic condition	Negative	Positive	Positive	Positive
44	5	Negative	Negative	Positive	Positive	Positive
65	5	Papillary UBC pTaG2	Negative	Negative	Not performed	Positive
86	5	Dysplastic condition	Negative	Positive	Positive	Positive
91	5	Negative	Negative	Positive	Positive	Negative
110	4	Negative	Negative	Positive	Positive	Positive
117	4	Negative	Negative	Positive	Not performed	Negative
148	5	Papillary infiltrating UBC pT3bN1G3	Hyper-dysplasia	Negative	Not performed	Positive
152	5	Phlogosis	Negative	Positive	Negative	Negative
178	5	Negative	Negative	Positive	Positive	Positive
207	5	Dysplastic condition	Negative	Positive	Positive	Positive