Polymorphisms at Amino Acid Residues 141 and 154 Influence Conformational Variation in Ovine PrP
Figure 3
CD spectra of sarkosyl-treated ovine recombinant PrP. Conformational changes of (a) ALRQ; (b) AFRQ; or (c) ALHQ ovine recombinant PrP following treatment with water (continuous line); 0.005% sarkosyl (large dashed line); or 0.008% sarkosyl (small dashed line). Data shown are representative CD spectra for different batches of ovine recombinant PrP ALRQ (); AFRQ (); and ALHQ ().
