Research Article

miR-375 Suppresses IGF1R Expression and Contributes to Inhibition of Cell Progression in Laryngeal Squamous Cell Carcinoma

Figure 5

Transwell invasion assay. (a) Upregulation of miR-375 in SNU-46 cells significantly inhibited invasion compared with the control group. (b) Invasion of SNU-899 cells was inhibited when cells were transfected with miR-375 mimics compared with miR-NC. Cells on the bottom of the invasion chamber were fixed, stained, and photographed, and the number of cells was counted. The results are expressed as mean ± SD of three independent experiments. () Significant difference when compared with the miR-NC group ().
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(a)
374598.fig.005b
(b)