Research Article

Identifying Dynamic Protein Complexes Based on Gene Expression Profiles and PPI Networks

Algorithm 2

The description of algorithm DPC.
Algorithm DPC
Input: : a PPI network; Ge: gene expression data;
: the threshold of gene expression; : the threshold of density.
Output: PC: protein complexes
(1) Call DetectingPPC;
(2)  ;
(3) For each node   do
     For all do
       Compute ;
       if then
       CL( );
(4) For each time course   do
     For each node   do
       if Ge
         ;
         ;
     For each core   do
       PC = PC ;
(5) Filtering PC
(6) Output PC