Methylation-Associated Gene Silencing of RARB in Areca Carcinogens Induced Mouse Oral Squamous Cell Carcinoma

Table 2

The selected gene list of hypermethylation.

Accession number	Gene symbol	Description	Functions	Related carcinoma types
S80555	RARB	Retinoic acid receptor-beta	DNA binding, ligand-dependent nuclear receptor activity	Nonsmall cell lung cancer, hepatoma, bladder cancer, rectal cancer, breast cancer, head and neck squamous cancer
AF069985	Nit1	Nitrilase homolog I	Hydrolase activity	Oral squamous cell carcinoma (in this study)
AL355176	BRCA2	Breast cancer II gene	Protein binding	Bladder cancer, breast cancer, ovarian cancer
AL928664	Hoxd4	Homeo box D4 gene	DNA binding	Breast cancer, leukemia, neuroblastoma
AF457187	p21	Cyclin-dependent kinase inhibitor IA	Cyclin-dependent protein kinase inhibitor activity	Nonsmall cell lung cancer, bladder cancer, breast cancer, ovarian cancer, medulloblastoma, hepatoma
M60348	MDR1	Multidrug-resistance protein gene	ATP binding, ATPase activity	Pancreatic cancer, breast cancer, colorectal cancer, glioblastoma, leukemia, laryngeal cancer cell
AB081498	ELYS	Embryonic large molecule derived from yolk sac	DNA binding	Oral squamous cell carcinoma (in this study)