Research Article
Carborane-Based Carbonic Anhydrase Inhibitors: Insight into CAII/CAIX Specificity from a High-Resolution Crystal Structure, Modeling, and Quantum Chemical Calculations
Table 3
CAII or CAIX residues interacting with 1, 2, and 3.
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| Interacting residues were identified from acrystal structure 4Q78 (this work); bcrystal structure 3IGP [34]; ccrystal structure 3PO6 [52]; dcomputational model (this work); eresidues making polar interactions are highlighted in bold. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||