Platelet-Rich Plasma in Bone Regeneration: Engineering the Delivery for Improved Clinical Efficacy

Table 3

Summary of studies which used PRP in its inactive form.

Authors	Study	Platelet concentration	Results
Nikolidakis et al. (2006) [27], Nikolidakis et al. (2008) [28]	CaP + Ti implants	8–12 × 10^5/𝜇L	Significantly increased bone contact percentage with Ti + PRP (liquid) implants; Significantly higher endosteal bone formation length in CaP + PRP (gel) coated implants
Yun et al. (2013) [31]	HA + BMMSCs + Ti implants	Adjusted to 1 × 10^6/𝜇L	No significance found
Chang et al. (2009) [32]	HA/collagen type I bone graft formation	9.25–12.5 × 10^5/𝜇L	Significant bone tissue in HA/collagen + PRP (liquid injection)
Han et al. (2009) [33]	DBM + active versus inactive PRP	8x over baseline*	PRP (liquid) significantly increased osteoconductivity of DBM

Note (*) that the study by Han et al. [33] did not give exact platelet counts.