Gender-Specific DNA Methylome Analysis of a Han Chinese Longevity Population

<table>General view of DNA methylation level for autosomes of Chinese nonagenarians/centenarians. The average genome-wide DNA methylation levels in male and female samples are represented using Circos. The inner and outer tracks indicate the average methylation levels for female and male samples, respectively. All autosomes are represented via 10 Mbp-wide windows. The average methylation level in each region represents the average <svg height="16.6625" id="M20" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 10 16.6625" width="10" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,12.162)"><path d="M558 587q0 -32 -14 -61t-40 -53.5t-48.5 -41t-54.5 -36.5q144 -51 144 -174q0 -55 -43.5 -108t-104.5 -87q-77 -42 -131 -42q-31 0 -54 20t-31 47l11 18q48 -29 108 -29q79 0 119.5 43t40.5 109t-44.5 107.5t-119.5 50.5l22 47q34 1 65 21q96 61 96 157q0 42 -24 67.5
t-62 25.5q-24 0 -43.5 -9t-35 -29.5t-27 -44t-22.5 -63t-19.5 -75.5t-18.5 -91q-57 -294 -68 -380q-26 -190 -35 -200q-26 -31 -97 -37l-4 26q19 9 48 170l77 413q23 121 52.5 187.5t83.5 114.5q70 62 148 62q51 0 88.5 -34t37.5 -91z" id="x1D6FD"></path></g>
</svg>-value (0-1) for all the probes in this region.</table>

BioMed Research International

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Figure 1

Figure 1: Gender-Specific DNA Methylome Analysis of a Han Chinese Longevity Population 