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BioMed Research International
Volume 2014, Article ID 396727, 9 pages
http://dx.doi.org/10.1155/2014/396727
Research Article

Gender-Specific DNA Methylome Analysis of a Han Chinese Longevity Population

1The Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing 100730, China
2Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China
3Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China
4University of Science and Technology Beijing, Beijing 100083, China
5Department of Neurology, Jiangbin Hospital, Nanning, Guangxi 530021, China
6Yongfu Committee of the Chinese People’s Political Consultative Conference, Yongfu, Guangxi 541800, China
7Department of Cardiothoracic Surgery, Guangxi Maternal and Child Health Hospital, Nanning, Guangxi 530003, China

Received 28 November 2013; Accepted 28 February 2014; Published 14 April 2014

Academic Editor: Jean X. Gao

Copyright © 2014 Liang Sun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1. DMGs detected in autosomes. Here, the methylation status represented the DMG types. A hypermethylated DMG (annotated as ‘+’) was defined if it only contains hypermethylated DMPs. Similarly, a hypomethylated gene (described as ‘-’), was defined if only hypomethylated DMPs were detected. If a gene contains both hypermethylated and hypomethylated DMPs, it was considered as a “mixed” DMG which was noted as ‘mixed’.

Table S2. Overlaps between DMGs and known human aging genes. This table shows the list of DMGs which overlapped with known aging genes in both autosomal and X chromosomes. The status showed the type of DMGs.

Table S3. Overlaps between autosomal DMGs and known disease genes. This table shows the overlaps between autosomal DMGs and known disease genes.

Table S4. Overlaps between DMGs in X chromosome and known disease genes. This table shows the Overlaps between DMGs in X chromosome and known disease genes.

  1. Supplementary Table S1
  2. Supplementary Table S2
  3. Supplementary Table S3
  4. Supplementary Table S4