Rho GTPase-Activating Protein 35 rs1052667 Polymorphism and Osteosarcoma Risk and Prognosis

Table 5

The rs1052667 polymorphism of ARHGAP35 and clinic pathological features of osteosarcoma.

Variable	rs1052667-CC		rs1052667-CT/TT		OS (95% CI)	𝑃
	𝑛	%	𝑛	%
Age (yrs)
≤26	80	60.2	81	71.1	1
>26	53	39.8	33	28.9	0.72 (0.39–1.35)	0.31
Gender
Female	49	36.8	44	38.6	1
Male	84	63.2	70	61.4	1.07 (0.61–1.89)	0.82
Race
Han	82	61.7	77	67.5	1
Minority	51	38.3	37	32.5	0.98 (0.54–1.77)	0.95
Tumor site
Femur	72	54.1	68	59.6	1
Tibia	30	22.6	21	18.4	0.66 (0.32–1.33)	0.24
Humeral bone	22	16.5	16	14	0.90 (0.40–2.01)	0.79
Others	9	6.8	9	7.9	0.91 (0.31–2.70)	0.86
Tumor size
≤5 cm	57	42.9	15	13.2	1
>5 cm	76	57.1	99	86.8	4.85 (2.51–9.37)	2.69×10^−6
Tumor grade
Low	68	51.1	23	20.2	1
High	65	48.9	91	79.8	4.07 (2.28–7.37)	2.14×10^−6
Metastasis
No	87	65.4	45	39.5	1
Yes	46	34.6	69	60.2	2.78 (1.63–4.76)	1.88×10^−4