The Human Plasma Membrane Peripherome: Visualization and Analysis of Interactions

Figure 4

Proteins are grouped based on their subcellular location in the network of the human plasma membrane peripheral proteins. 1: secreted proteins, 2: membrane proteins, 3: peripheral proteins, 4: cytoplasmic proteins, 5: nuclear proteins, 6: endomembrane system proteins, 7: mitochondrial proteins, and 8: lipid-anchored proteins. The membrane proteins of organelles and the endomembrane system are forming circles around the other proteins of the organelles. Proteins with unknown subcellular location are hidden in this view of the network.