ELFN1-AS1: A Novel Primate Gene with Possible MicroRNA Function Expressed Predominantly in Human Tumors

Figure 3

Transcribed locus Hs.633957 overview. A sketch of the chromosome 7 region containing transcribed locus Hs.633957 is shown according to the human genome assembly NCBI35/hg18. (A) Transcript variants are given to show the location of the region. (B) Repeating elements by RepeatMasker version 3.2.7 track indicates the location of repeating elements. (C) GC-box marks the GC-box motif identified in current study. HS sites mark position of the DNase I hypersensitivity sites. Location of the sites was estimated as averages of the left and right peak boundaries coordinates among the overlapping peaks from independent experiments for which data is available from UCSC Genome Browser (24 for HS1 and 17 for HS2). (D) Enhanced H3K27Ac, H3K4Me1, and Promoter H3K4Me3 tracks indicate association of the specific histone marks with the genome in certain cell lines. Overlaid data for several cell lines is shown. (E) ENCODE transcription factor ChIP-seq track provides a summary for association of various TFs with chromatin in various cell lines. Cell lines are indicated by letter code (H: HeLa-S3, K: K-562, h: HUVEC, g: GM12891, L: HepG2, G: GM12878). (F) Association of Pol 2 with chromatin in various cell lines is shown according to ENCODE ChIP-seq data. (G) ENCODE data on transcription levels in various cell lines are obtained by RNA-seq. Overlaid data is shown.