Research Article
Differentially Expressed MicroRNAs in Maternal Plasma for the Noninvasive Prenatal Diagnosis of Down Syndrome (Trisomy 21)
Table 3
Gene ontology categories of predicted miRNA targets (pathway union).
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Presented are KEGG GO terms for the 36 differentially expressed mature miRNAs identified by HT-qPCR (Table 2). Here, the results of pathway union are presented. The full list of GO terms identified by at least one miRNA is presented in Supplement 2. Pathways that have already been previously associated with Down syndrome pathologies were identified. These primarily include the mucin type O-glycan biosynthesis (related to -HCG), ECM-receptor interactions, and TGF- signaling. #: number of. |