Expression of Neuroendocrine Markers in Different Molecular Subtypes of Breast Carcinoma
Figure 3
Morphological features of luminal B carcinomas with neuroendocrine differentiation. (a) Solid (insular) formations of tumor cells. (b) Cribriform, DCIS-like areas of the same case. (c) Solid infiltrates of plasmacytoid tumor cells with subnuclear eosinophilic cytoplasm. (d) Same case with focal mucinous differentiation. (e) Infiltrative border of a carcinoma with scattered tumor cells. (f) The same case with focal rosette-like structures. (g) Prominent peritumoral clefts, imparting a micropapillary-like morphology, (h) The same case with perifocal high-grade DCIS with only focal expression of chromogranin A.
