On the Coupling of Two Models of the Human Immune Response to an Antigen

Table 5

Sensitivity analysis—chosen parameters, description, and the maximum error value.

Parameter	Description	Maxerr
𝛾𝐴𝑀	Macrophage activation rate	6.47
𝛼𝐹	Antibodies migration rate	6.36
𝑀𝑅0	Resting macrophage initial condition	6.17
𝛽𝐴	Antigen replication rate	5.67
𝜌𝐹	Antibodies release rate	5.15
𝑘𝐴	Antigen carrying capacity coefficient	4.82
𝑏^𝑃𝑃	B cell expenditure to become plasma cell	4.09
𝛼𝑀𝐴	Activated macrophage migration rate	4.09
𝜆𝐴𝐹∣𝑀𝐴	Activated macrophage phagocytosis rate of opsonized antigen	4.06
𝑏𝑃	T cell expenditure to stimulate B cell	2.42
𝐷𝑀𝑅	Resting macrophage diffusion coefficient	0.93
𝐷𝐴	Antigen diffusion coefficient	0.85
𝜆𝑀𝐴	Activated macrophage phagocytosis rate	0.76
𝑏^𝐵𝑃	B cell stimuli coefficient	0.73
𝐷𝑀𝐴	Activated macrophage diffusion coefficient	0.24
𝐴0	Antigen initial condition	0.09
𝛼𝑀𝑅	Resting macrophage source coefficient	0.07
𝜆𝑀𝑅	Resting macrophage phagocytosis rate	0.05
𝜆𝐴𝐹∣𝑀𝑅	Resting macrophage phagocytosis rate of opsonized antigen	0.01
𝑏𝑇	T cell stimuli coefficient	3∗10^−4