Primary Genetic Investigation of a Hyperlipidemia Model: Molecular Characteristics and Variants of the Apolipoprotein E Gene in Mongolian Gerbil

Table 4

Association analysis between SNP genotypes and recorded traits

	Body weight	CHO	HDL	LDL	TG
	𝑋 ± SD	𝑋 ± SD	𝑋 ± SD	𝑋 ± SD	𝑋 ± SD
Gender
♀	76.2 ± 21.9^B	104.8 ± 69.2^b	31.2 ± 23.5^b	50.3 ± 42.6	648.5 ± 491.3^b
♂	103.9 ± 25.0^A	129.6 ± 78.5^a	36.2 ± 34.6^a	46.5 ± 31.0	758.3 ± 527.7^a
Age
<8 months	77.5 ± 23.8^B	92.1 ± 35.6^c	28.1 ± 6.9^B	46.5 ± 38.7^B	491.2 ± 263.8^B
9–17 months	106.8 ± 22.3^A	150.1 ± 98.2^b	41.9 ± 49.6^A	46.5 ± 31.0^B	1046.8 ± 595.2^A
18–26 months	104.8 ± 20.9^A	173.3 ± 114.1^a	46.2 ± 41.5^A	65.8 ± 38.7^A	1172.4 ± 680.4^A
C97T
CC	88.0 ± 26.7^B	114.5 ± 73.5^B	33.5 ± 30.8	46.5 ± 27.1	705.1 ± 490.7^b
CT	62.7 ± 5.5^C	75.0 ± 15.9^B	24.2 ± 1.5	31.0 ± 7.7	245.5 ± 210.3^c
TT	110.1 ± 32.3^A	167.9 ± 104.0^A	38.5 ± 16.9	61.9 ± 34.8	1001.1 ± 732.6^a
G781T
GG	113.3 ± 33.2^A	200.4 ± 138.1^A	54.2 ± 58.1^A	73.5 ± 42.6^A	1025.5 ± 714.8^A
GT	86.4 ± 26.0^B	109.5 ± 68.5^B	31.9 ± 23.5^B	46.5 ± 38.7^B	669.1 ± 487.5^B
TT	106.7 ± 22.7^A	163.2 ± 106.4^A	70.8 ± 108.8^A	58.1 ± 34.8^A	1136.0 ± 651.6^A
A1774T
AA	84.9 ± 22.7	106.4 ± 54.2	39.6 ± 49.2	46.5 ± 46.5	486.5 ± 359.4^a
AT	85.6 ± 26.2	115.7 ± 78.9	33.5 ± 30.0	50.3 ± 42.6	701.0 ± 529.4^b

∗Estimated value is the least squares mean ± SD. Different lowercase letters a, b, and c indicate significant difference at 0.05 level; uppercase letters A, B, and C indicate significant difference at 0.01 level.