Table 1: Score for clinical parameters (on a scale from 0 to 3, maximum total score 87) in dogs with CanL.

Clinical sign0123

AppetiteNormalSlight decreaseModerate decreaseAnorexia
MentationNormalSlight depressionDepressionProstration
Exercise intoleranceNoSlightModerateRefusal to move
Weight lossNoSlightModerateSevere
PolyuriaNoSlightModerateSevere
PolydipsiaNoSlightModerateSevere
UP/UCNo<1>1 < 2>2
Localized muscle atrophy (temporal muscles)NoSlightModerateSevere
Generalized muscle atrophyNoSlightModerateSevere
LymphadenomegalyNo1-2 nodes>2 < 4 nodesGeneralized
SplenomegalyNoYes
Conjunctivitis and/or blepharitisNoUnilateral and slightBilateral or unilateral severeBilateral and severe
Uveitis and/or keratitisNoUnilateral and slightBilateral or unilateral severeBilateral and severe
Pale mucous membranesNoSlightModerateSevere
EpistaxisNever presentedSporadicFrequentPersistent
Mouth ulcers or nodulesNo1 or 2 small ulcers or nodules>2 small ulcers or nodules >1/4 of oral cavity covered by ulcers or nodules
VomitingNoSporadicFrequentFrequent with blood
DiarrheaNoSporadicFrequentPersistent
LamenessNoSporadicFrequentConstant
ErythemaNo<10% body surface or slight generalized erythema10–25% body surface or moderate generalized erythema>25% body surface
Dry exfoliative dermatitisNo<10% body surface or slight generalized erythema10–25% body surface or moderate generalized erythema>25% body surface
Ulcerative dermatitisNo1-2 ulcers3–5 ulcers>5 ulcers
Nodular dermatitisNo1-2 nodules3–5 nodules>5 nodules
Sterile pustular dermatitisNo1-2 pustules3–5 pustules>5 pustules
AlopeciaNo<10% body surface10–25% body surface erythema>25% body surface
Altered pigmentationNoLocalizedMultifocalGeneralized
Hyperkeratosis truffle and padsNoSlightModerateSevere
Generalized hyperkeratosisNoSlightModerateSevere
OnychogryphosisNoSlightModerateSevere