Comparison of Host Immune Responses to Homologous and Heterologous Type II Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Challenge in Vaccinated and Unvaccinated Pigs
Figure 2
Serum neutralizing antibody titer is associated with PRRSV vaccination-induced protection against homologous and heterologous challenge. (a) PRRSV-specific antibodies were detected in the serum using IDEXX ELISA kit. The threshold for positive sera was set at a sample to positive () ratio of 0.4 according to the manufacturer’s instructions. ((b)–(d)) Serum samples were titrated on MARC-145 cells and the levels of anti-PRRSV neutralizing Abs were determined as the reciprocal of the highest dilution that could inhibit CPE. Data were shown as mean ± SEM for 5 pigs per group. *.
