Caspase-14 Expression Impairs Retinal Pigment Epithelium Barrier Function: Potential Role in Diabetic Macular Edema

Figure 2

Overexpression of caspase-14 in ARPE-19 cells. Western blot analysis of caspase-14 in ARPE-19 cells transfected with pCMV plasmid encoding human caspase-14 cDNA showed a remarkable increase in the levels of caspase-14 compared with cells expressing the empty vector (𝑛=4; ^∗𝑃<0.0001).