BioMed Research International / 2014 / Article / Tab 3

Research Article

Survey on Knowledge, Attitudes, and Training Needs of Italian Residents on Genetic Tests for Hereditary Breast and Colorectal Cancer

Table 3

Sociodemographic and professional characteristics associated with knowledge on genetic testing for breast cancer (BRCA1/BRCA2 mutations) and colorectal cancer (APC mutations).

Breast cancerColorectal cancer
OR95% CIOR adj*95% CIOR95% CIOR adj 95% CI

Gender
 Female1.001.001.001.00
 Male0.530.34–0.830.550.35–0.871.240.74–2.061.360.80–2.31
Age
 <281.001.001.001.00
 28-290.720.39–1.320.660.35–1.240.780.42–1.430.740.39–1.41
 30-310.700.36–1.370.620.31–1.260.320.14–0.730.250.10–0.61
 ≥320.710.33–1.540.680.30–1.560.390.15–0.990.330.12–0.92
Personal or family history of breast or colon cancer
 No1.001.001.001.00
 Yes1.400.77–2.571.210.65–2.250.980.52–1.860.910.47–1.77
Professional area~
 Medicine1.001.001.001.00
 Surgery0.600.31–1.170.800.39–1.641.100.50–2.401.240.55–2.80
 Others1.160.72–1.871.200.74–1.960.900.52–1.550.880.50–1.55
Clinical activity
 No1.001.001.001.00
 Yes0.940.59–1.500.970.60–1.570.930.55–1.581.020.59–1.76
Exposure to cancer genetic testing during graduate training
 No1.001.001.001.00
 Yes1.731.06–2.821.721.05–2.822.011.05–3.842.081.07–4.03
Postgraduate training courses in epidemiology and EBM
 No1.001.001.001.00
 Yes0.900.50–1.610.88 048–1.601.851.01–3.451.951.03–3.69
Patient request of cancer genetic tests in the previous yeari
 No1.001.001.001.00
 Yes2.151.05–4.381.840.89–3.830.900.42–1.920.840.38–1.84
Hours per week dedicated to continuing medical education
 <11.001.001.001.00
 1–51.450.76–2.751.390.71–2.731.310.57–3.000.980.41–2.30
 6–102.030.93–4.412.110.93–4.771.640.65–4.141.250.48–3.29
 >101.730.61–4.961.840.62–5.431.320.38–4.560.740.19–2.91
Promotional material about breast or colon cancer received in the previous year
 No1.001.001.001.00
 Yes1.290.65–2.561.120.56–2.250.670.25–1.820.410.14–1.25

OR: odds ratio; CI: confidence interval; EBM: evidence based medicine.
*OR adjusted by professional area, exposure to cancer genetic testing during graduate training.
OR adjusted by gender, postgraduate training courses about epidemiology and EBM.
~List of specializations according to each area is available in Supplementary file S1.
iIncluded physicians with clinical activity.