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BioMed Research International
Volume 2014 (2014), Article ID 419376, 8 pages
http://dx.doi.org/10.1155/2014/419376
Research Article

Through Diffusion Tensor Magnetic Resonance Imaging to Evaluate the Original Properties of Neural Pathways of Patients with Partial Seizures and Secondary Generalization by Individual Anatomic Reference Atlas

1Department of Electrical Engineering, National Central University, Jhongli, Taoyuan 32001, Taiwan
2Epilepsy Center, Buddhist Tzu Chi General Hospital, Hualian, Hualian 97002, Taiwan
3Biomedical Electronics Translational Research Center, National Chiao Tung University, Hsinchu 30010, Taiwan
4Department of Neurology, Chung Shan Medical University and Chung Shan Medical University Hospital, Taichung 40201, Taiwan

Received 25 December 2013; Revised 4 April 2014; Accepted 6 April 2014; Published 5 May 2014

Academic Editor: Carl Muroi

Copyright © 2014 Syu-Jyun Peng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Sixteen patients having neocortical seizures with secondarily generalised convulsions and 16 age-matched normal subjects were imaged with high-resolution and diffusion tensor MRIs. Automated demarcation of supratentorial fibers was accomplished with personalized fiber-labeled atlases that were generated by transforming a template atlas to align with the individual brain images. Using the independent-samples t-test, the MD and FA values in the patient group were compared with those in the control group, as well as within the patient subgroups for the WM structures studied.

Supplementary Table 1: shows the comparisons between the patient and normal groups in terms of MD and FA in white matter integrity.

Supplementary Table 2: shows the number of voxels in the different fibers of the normal subjects.

Supplementary Table 3: shows the comparisons between the patients with two different onset age subgroups and normal groups in terms of MD and FA in white matter integrity.

Supplementary Table 4: shows the comparisons between the patients with drug-resistant and drug-effective subgroups and normal groups in terms of MD and FA in white matter integrity.

  1. Supplementary Tables