Research Article

Micronuclei in Bone Marrow and Liver in relation to Hepatic Metabolism and Antioxidant Response due to Coexposure to Chloroform, Dichloromethane, and Toluene in the Rat Model

Table 2

Doses administered per treatment.

Group of treatmentDoses

Neg. control (corn oil)*125  L/kg b.w.5
TOL/DCM/CLF
 Low-mix* 2.0/0.6/0.655
 Mid-mix* 4.0/1.2/1.35
 High-mix* 8.0/2.5/2.65

Positive controls
 tSBO2.03
 CCl410.03
 BEN12.03
 DEN1.03

These were the daily doses administered for one day or three days of the mixture.
(mmol/kg b.w.).
BEN and DEN were administered for two days; CCl4 and tSBO, for three days.
refers to animals used in either regime of treatment.