Effects of Single Pill-Based Combination Therapy of Amlodipine and Atorvastatin on Within-Visit Blood Pressure Variability and Parameters of Renal and Vascular Function in Hypertensive Patients with Chronic Kidney Disease

Table 4

Effects of single-pill amlodipine/atorvastatin-based therapy on renal and vascular functions.

	Baseline	Week 16
Renal function
Serum creatinine (mg/dL)	1.04±0.44	1.09±0.50
eGFR (mL/min/1.73 m^2)	60.4±25.7	58.8±25.6
UACR (mg/g-Cr)	1034±1480	733±1218^∗
Serum cystatin C (mg/L)	1.30±0.45	1.31±0.49
Vascular function
baPWV (cm/s)	1903±353	1786±382^∗
AI (%)	84±15	81±14
cSBP (mmHg)	148±19	129±23^∗∗

Values are means ± SD. eGFR: estimated glomerular filtration rate; UACR: urine albumin-to-creatinine ratio; baPWV: brachial-ankle pulse wave velocity; AI: augmentation index; cSBP: central systolic blood pressure.
^∗𝑃<0.05, ^∗∗𝑃<0.01.