Research Article

Comparison of the Freiburg and Charlson Comorbidity Indices in Predicting Overall Survival in Elderly Patients with Newly Diagnosed Multiple Myeloma

Table 5

Serious adverse events (AEs).

(%)
Grade 0–3Grade 4-5

Hematologic AE
Anemia103 (87.3%)15 (12.7%)
Neutropenia103 (87.3%)15 (12.7%)
Thrombocytopenia114 (92.2%) 4 (7.8%)
Febrile neutropenia113 (90.8%) 5 (9.2%)

Grade 0–2Grade 3–5

Nonhematologic AE
Infection83 (70.0%)35 (30.0%)
Diarrhea/constipation105 (89.0%)13 (11.0%)
Fatigue117 (90.7%)11 (9.3%)
Sensory neuropathy108 (91.5%)10 (8.5%)
Nausea/vomiting111 (94.1%)7 (5.9%)
Azotemia112 (94.9%) 6 (5.1%)

Grade ≥4 hematologic AE 27 (22.9%)
Grade ≥3 nonhematologic AE59 (50.0%)
Grade 5 AE8 (6.8%)