Research Article

Early Trypanosoma cruzi Infection Reprograms Human Epithelial Cells

Table 1

Overexpressed genes with fold change ≥10 at any time postinfection ( ).

Gene IDDescriptionFC- FC- FC-

Immune response
 CCL20 Chemokine (C-C motif) ligand 20 85,293,314,5
 CCL8 Chemokine (C-C motif) ligand 8 39,923,13,1
 CD96 CD96 molecule27,424,424,2
 CXCL1 Chemokine (C-X-C motif) ligand 1 20,018,97,6
 CXCL2 Chemokine (C-X-C motif) ligand 2 49,812,36,2
 CXCL3 Chemokine (C-X-C motif) ligand 3 64,912,74,1
 EREG Epiregulin9,213,84,1
 IL1A Interleukin 1, alpha18,06,32,3
 IL6 Interleukin 6 27,36,92,6
 IL8 Interleukin 8 326,967,916,6
 OLR1 Oxidized low density lipoprotein (lectin-like) receptor 1 16,224,914,7
 PTX3 Pentraxin 3, long13,813,19,3
Apoptosis inhibition
 BCL2A1 BCL2-related protein A1 16,427,48,2
 BIRC3 Baculoviral IAP repeat containing 3 23,67,22,8
Transcription
 LMO2 LIM domain only 2 (rhombotin-like 1) 11,612,44,6
 MYCL1 V-myc myelocytomatosis viral oncogene homolog 1 2,25,510,7
 RELB V-rel reticuloendotheliosis viral oncogene homolog B 11,09,35,0
Signalling
 RGR Retinal G protein coupled receptor 20,724,120,4
 PRKG1 Human mRNA for type I beta cGMP-dependent protein kinase 22,227,724,0
Binding
 MUC4 Mucin 4, cell surface associated1,910,74,5
 SDC4 Syndecan 4 11,47,72,5
 STATH Statherin10,713,210,9
Transport
 SLC9A6 Solute carrier family 9 (sodium/hydrogen exchanger), member 6 12,713,711,3
Fatty acid synthesis
 ELOVL7 ELOVL fatty acid elongase 7 10,810,35,1
Stress response
 SOD2 Superoxide dismutase 2, mitochondrial15,23,33,2
Other
 TCL6 T-cell leukemia/lymphoma 6 (nonprotein coding) 28,428,326,1
 TNIP3 TNFAIP3 interacting protein 3 19,428,910,6
 WFDC10A WAP four-disulfide core domain 10A 3,210,010,1
 NCRNA00246A nonprotein coding RNA 246A 10,011,911,3
 LOC283174 Hypothetical LOC283174 44,339,940,4
 FLJ44715 cDNA FLJ44715 fis 18,821,019,6
 A1BG cDNA FLJ31639 fis 29,139,130,8
 ART3 ADP-ribosyltransferase 3 2,25,812,5