Research Article
Association of P2Y12 Gene Promoter DNA Methylation with the Risk of Clopidogrel Resistance in Coronary Artery Disease Patients
Table 7
Logistic regression analysis with nongenetic and genetic factors in total population.
| Variables | | value | Exp () | 95% C.I. |
| P2Y12 CpG1 | −0.141 | 0.096 | 0.869 | 0.74–1.03 | P2Y12 CpG2 | 0.169 | 0.142 | 1.184 | 0.95–1.49 | Age | 0.047 | 0.163 | 1.048 | 0.98–1.12 | Gender (male) | −0.591 | 0.399 | 0.554 | 0.14–2.19 | Hypertension | 0.569 | 0.324 | 1.767 | 0.57–5.47 | DM | −0.979 | 0.282 | 0.376 | 0.06–2.24 | Dyslipidemia | −0.538 | 0.395 | 0.584 | 0.17–2.02 | Current smoking | −0.378 | 0.573 | 0.685 | 0.18–2.55 | Alcohol abuse | 1.010 | 0.214 | 2.746 | 0.56–13.51 | BMI | −0.073 | 0.514 | 0.930 | 0.75–1.16 | Stent | 0.865 | 0.009 | 2.374 | 1.24–4.53 | LEVF | −0.035 | 0.368 | 0.965 | 0.89–1.04 | TC | 0.093 | 0.847 | 1.097 | 0.43–2.82 | Triglycerides | 0.081 | 0.770 | 1.084 | 0.63–1.86 | HDL | −1.283 | 0.308 | 0.277 | 0.02–3.27 | LDL | −0.408 | 0.481 | 0.665 | 0.21–2.07 | GLU | 0.681 | 0.013 | 1.976 | 1.15–3.39 | HbAC1 | −0.907 | 0.022 | 0.404 | 0.19–0.88 | ALT | −0.009 | 0.541 | 0.992 | 0.97–1.02 | AST | 0.002 | 0.366 | 1.002 | 1.00–1.01 | TBIL | −0.036 | 0.357 | 0.965 | 0.89–1.04 | A | −0.091 | 0.264 | 0.913 | 0.78–1.07 | BUN | −0.161 | 0.292 | 0.851 | 0.63–1.15 | CR | −0.004 | 0.825 | 0.996 | 0.97–1.03 | UA | 0.002 | 0.455 | 1.002 | 1.00–1.01 | CRP | −0.007 | 0.677 | 0.993 | 0.96–1.03 | PLT | 0.008 | 0.712 | 1.008 | 0.97–1.05 | MPV | 0.380 | 0.507 | 1.462 | 0.48–4.50 | PCT | −13.635 | 0.639 | 0.000 | 0.00–6.71 | PDW | −0.183 | 0.736 | 0.832 | 0.29–2.42 | Constant | 8.480 | 0.469 | 4815.697 | |
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