Research Article

Association of P2Y12 Gene Promoter DNA Methylation with the Risk of Clopidogrel Resistance in Coronary Artery Disease Patients

Table 7

Logistic regression analysis with nongenetic and genetic factors in total population.

Variables valueExp ( )95% C.I.

P2Y12 CpG1−0.141 0.096 0.869 0.74–1.03
P2Y12 CpG20.169 0.142 1.184 0.95–1.49
Age0.047 0.163 1.048 0.98–1.12
Gender (male)−0.591 0.399 0.554 0.14–2.19
Hypertension0.569 0.324 1.767 0.57–5.47
DM−0.979 0.282 0.376 0.06–2.24
Dyslipidemia−0.538 0.395 0.584 0.17–2.02
Current smoking−0.378 0.573 0.685 0.18–2.55
Alcohol abuse1.010 0.214 2.746 0.56–13.51
BMI−0.073 0.514 0.930 0.75–1.16
Stent0.865 0.009 2.374 1.24–4.53
LEVF−0.035 0.368 0.965 0.89–1.04
TC0.093 0.847 1.097 0.43–2.82
Triglycerides0.081 0.770 1.084 0.63–1.86
HDL−1.283 0.308 0.277 0.02–3.27
LDL−0.408 0.481 0.665 0.21–2.07
GLU0.681 0.013 1.976 1.15–3.39
HbAC1−0.907 0.022 0.404 0.19–0.88
ALT−0.009 0.541 0.992 0.97–1.02
AST0.002 0.366 1.002 1.00–1.01
TBIL−0.036 0.357 0.965 0.89–1.04
A−0.091 0.264 0.913 0.78–1.07
BUN−0.161 0.292 0.851 0.63–1.15
CR−0.004 0.825 0.996 0.97–1.03
UA0.002 0.455 1.002 1.00–1.01
CRP−0.007 0.677 0.993 0.96–1.03
PLT0.008 0.712 1.008 0.97–1.05
MPV0.380 0.507 1.462 0.48–4.50
PCT−13.635 0.639 0.000 0.00–6.71
PDW−0.183 0.736 0.832 0.29–2.42
Constant8.480 0.469 4815.697