Research Article
Increased Release Time of Antibiotics from Bone Allografts through a Novel Biodegradable Coating
Table 4
Calculated antibiotic content of the coated bone compared to the daily doses in clinical practice.
| | 24 hours from 0.05 g bone | 28th day from 0.05 g bone | 24 hours from 45 g bone | 28th day from 45 g bone | Daily dose/reference (mg/day) |
| Amoxicillin (mg) | 0.26 | | 234 | |
6000 [33] | % of daily dose | 0.004 | | 3.9 | |
| Ciprofloxacin (mg) | 0.674 | 0.015 | 606.72 | 13.03 |
1500 [34] | % of daily dose | 0.045 | 0.001 | 40.45 | 0.87 |
| Vancomycin (mg) | 0.485 | 0.05 | 436.87 | 44.68 |
1000 [35] | % of daily dose | 0.049 | 0.005 | 43.687 | 4.468 |
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