Modulation of Steroidogenic Pathway in Rat Granulosa Cells with Subclinical Cd Exposure and Insulin Resistance: An Impact on Female Fertility
Figure 3
Effect of dexamethasone and Cd either alone or in combination on insulin resistance in terms of (a) serum insulin levels, (b) FIRI, and (c) protein expression of insulin receptor in granulosa cell lysate using beta actin as internal control in rats. The values are represented as mean ± SEM of three independent observations (). Serum insulin levels and FIRI were significantly increased ( and ###) in Dexa group as compared to control and Cd group. Dexa + Cd also showed significant increase ( and ###) in serum insulin and FIRI as compared to control and Cd group. Dexa = dexamethasone.
